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Updated: May 29, 2025

Advanced Glycation End-Products Sensitize Human Sensory-Like Neuron Cells to Capsaicin-Induced Calcium Influx
06:05

Advanced Glycation End-Products Sensitize Human Sensory-Like Neuron Cells to Capsaicin-Induced Calcium Influx

Published on: May 2, 2025

348

小分子介导的向蛋白质降解与疼痛有关的电压通道

Alexander Chamessian, Maria Payne, Isabelle Gordon

    bioRxiv : the preprint server for biology
    |February 3, 2025
    PubMed
    概括

    包括PROTACs在内的小分子降解剂可以有效地准像NaV1.8和NaV1.7这样的电压通道 (VGSCs) 进行降解. 这为开发非成性疼痛治疗方法开辟了新的途径.

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