重新思考组织学幻灯片数字化低资源设置的工作流程
Talat Zehra1, Joseph Marino2, Wendy Wang2
1Jinnah Sindh Medical University, Karachi, Pakistan.
概括
一个新的云工作流从廉价的显微镜视频创建高质量的全幻灯片图像 (WSIs). 这使得数字病理学成为远程咨询和人工智能分析的民主化,改善了全球卫生公平.
科学领域:
- 数字病理学数字病理学
- 医疗成像医学成像
- 医疗信息学 医疗信息学
背景情况:
- 组织学幻灯片数字化对于远程病理学,教育和人工智能应用至关重要.
- 目前的数字化方法昂贵,限制了资源有限的环境中的访问,并加剧了健康不平等.
- 高成本源于专门的扫描仪,存储和人员,以及用于手动扫描的先进硬件.
研究的目的:
- 开发一种可访问的基于云的工作流程,用于创建高质量的全幻灯片图像 (WSIs).
- 通过廉价显微镜捕获的低质量的视频来实现扫描器质量的WSI生成.
- 降低在服务不足的地区采用数字病理学的成本障碍.
主要方法:
- 一个云平台处理上传的低质量的显微镜视频.
- 一个管道将图像拼接起来,模糊了焦点外的区域,并将样本升级到40X分辨率.
- 图像处理纠正亮度,对比度和照明变化.
主要成果:
- 在产生WSIs的有效性已被证明,用于被忽视的热带疾病,如皮肤莱什曼病.
- 从各种常见病理中成功创建了WSI,包括乳腺,肝脏,胃,淋巴结和十二指肠核心活检.
- 工作流程有效地将低成本的视频输入转化为具有诊断价值的全幻灯片图像.
结论:
- 开发的工作流大大降低了数字幻灯片创建的成本.
- 这项创新提高了数字病理学工具的可访问性,用于全球的远程病理学和知识共享.
- 该项目旨在通过提供负担得起的数字病理学解决方案来弥合健康公平差距.
相关概念视频
Downsampling
872
When considering a sampled sequence with zero values between sampling instants, one can replace it by taking every N-th value of the sequence. At these integer multiples of N, the original and sampled sequences coincide. This process, known as decimation, involves extracting every N-th sample from a sequence, thereby creating a more efficient sequence.
The Fourier transform of the decimated sequence reveals a combination of scaled and shifted versions of the original spectrum. This...
The Fourier transform of the decimated sequence reveals a combination of scaled and shifted versions of the original spectrum. This...
872
Block Diagram Reduction
727
The process of deriving the transfer function of a control system often involves reducing its block diagram to a single block. This simplification can be achieved through a series of strategic operations, including relocating branch points and comparators. These operations preserve the overall function of the system while allowing for easier manipulation and combination of blocks.
The first step in this process is the identification and relocation of a branch point. A branch point, where a...
The first step in this process is the identification and relocation of a branch point. A branch point, where a...
727


