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对一些埃及省份的反动物血病及其相关风险因素的综合流行病学评估

Nesreen Allam Tantawy Allam¹, Mahinour Ezzeldin Abdelsalam², Hend I Elsharkawy³

¹Department of Parasitology and Animal Diseases, Veterinary Research Institute, National Research Centre, 33 El Buhouth Street, Dokki, P.O. Box: 12622, Cairo, Egypt.

Veterinary world

|February 3, 2025

概括

由Brucella melitensis biovar 3引起的病在埃及普遍存在,导致了重大的经济损失. 使用分子方法进行早期检测对于有效的控制计划至关重要.

科学领域:

兽医医学兽医医学兽医医学
流行病学流行病学
分子生物学分子生物学

背景情况:

血病会通过堕胎,不孕症和减少牛奶产量,在反动物中造成巨大的经济损失.
这项研究探讨了埃及反动物血病的流行率和风险因素,强调了早期检测携带者以进行控制.

研究的目的:

为了估计在埃及六个省份的反动物血病的流行率.
评估与布鲁塞洛症流行病学状况相关的风险因素.
突出早期携带者检测对于成功的控制计划的重要性.

主要方法:

通过使用血清学测试 (BAPAT,RBPT,CFT) 和分子类型 (AMOS-PCR) 调查了3000只反动物.
进行了血液生物化学分析,基因毒性测定和组织病理学检查.
评估血清微量元素,氧化应激和急性阶段蛋白与身体状况评分 (BCS) 相比.

主要成果:

布鲁塞拉梅利坦尼斯生物菌3被证实是流行的菌株.
总体血清阳性在不同测试中从5.1%到6.1%不等.
低BCS组显示器官功能障碍,营养不良和DNA损伤的显著指标.
组织病理学揭示了颗粒状病变和胎盘亡;在白细胞中检测到染色体异常.

结论:

布鲁塞拉梅利坦尼斯 (Brucella melitensis biovar 3) 是埃及反动物中布鲁塞洛症的主要原因.
混合养系统增加了跨物种传播的风险.
目前的血清诊断有局限性;需要分子技术进行早期和准确的检测,以改善控制策略.

关键词:

这是AMOS-PCR的结果.布鲁塞拉梅利坦尼斯 (Brucella melitensis) 是一种植物.埃及埃及埃及埃及堕胎堕胎堕胎堕胎堕胎堕胎堕胎堕胎急性阶段蛋白质的急性阶段蛋白质.身体状况得分身体状况得分遗传毒性遗传毒性遗传毒性遗传毒性乳腺炎是一种乳腺炎.氧化应激是一种氧化应激.患病率的流行情况.微量元素的微量元素是什么

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