无烟,不无害:了解纳斯瓦尔在巴基斯坦西北部的心血管风险
Ihsanur Rahman1, Fayaz Ahmad1, Naveed Sadiq1
1Institute of Public Health and Social Sciences, Khyber Medical University, Peshawar, Pakistan.
无烟烟草产品纳斯瓦尔 (Naswar) 的使用与冠状动脉疾病 (CAD) 的几率增加有显著关联. 这包括更长的使用时间,特定的使用行为,如浸泡和吐,以及纳斯瓦尔的黑色品种.
科学领域:
- 心血管疾病研究研究
- 烟草控制研究研究研究
- 公共卫生调查 公共卫生调查
背景情况:
- 吸烟是导致死亡的主要原因,特别是冠状动脉疾病 (CAD).
- 无烟烟草 (SLT) 产品,如巴基斯坦普遍存在的纳斯瓦尔,需要进一步调查其心血管风险.
- 全球卫生组织强调需要对各种SLT产品进行研究,以及它们对不同人群的CAD的影响.
研究的目的:
- 调查纳斯瓦使用与冠状动脉疾病 (CAD) 患病率之间的关联.
- 探索纳斯瓦尔消费的特定模式及其与CAD风险的相关性.
- 为监管SLT产品提供证据,以减轻心血管风险.
主要方法:
- 进行了一项病例对照研究,涉及112例CAD病例和112例对照.
- 在2021年7月至2022年8月期间,通过采访采用预先结构化的问卷收集数据.
- 使用多变量逻辑回归分析来确定纳斯瓦尔-CAD关联的赔率比率.
主要成果:
- 纳斯瓦尔使用者对CAD的调整后几率显著更高 (OR:2.56).
- 特定的使用因素,如浸泡时间 (OR: 3.77),使用时间 (OR: 4.30),黑色纳斯瓦尔 (OR: 2.62) 和唾液吐 (OR: 3.76),与增加CAD几率有关.
- 在病例和对照之间观察到年龄,收入,家族心脏病史和并发症之间的统计学上显著差异.
结论:
- 纳斯瓦尔的使用与冠状动脉疾病的风险增加有关.
- 研究结果强调,迫切需要针对纳斯瓦尔等SLT产品的监管措施,以减少心血管疾病负担.
- 需要进一步的研究,以了解将纳斯瓦尔消费与CAD联系在一起的具体机制.
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