睡眠时间与非酒精性脂肪肝疾病风险之间的关联:系统性审查和元分析
Kasra Pirahesh1, Ali Zarrinnia2, Leila Nikniaz3
1Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Preventive medicine reports
|February 3, 2025
概括
长时间或短时间的睡眠时间可能会影响非酒精性脂肪肝疾病 (NAFLD). 这次元分析发现,睡眠时间最高的类别与较低的NAFLD风险有关,但没有发现剂量反应关系.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 非酒精性脂肪肝 (NAFLD) 是一个日益严重的全球健康问题.
- 睡眠时间不足和过度都与NAFLD有关.
- 了解睡眠模式和NAFLD之间的准确关系对于公共健康至关重要.
研究的目的:
- 进行关于睡眠时间和NAFLD之间的关联的元分析.
- 分析睡眠时间和NAFLD之间的剂量反应关系.
- 为了比较NAFLD患者和健康个体之间的平均睡眠时间.
主要方法:
- 观察性研究的系统审查和元分析.
- 在PubMed,Scopus和Web of Science数据库中搜索到2023年11月.
- 包括31项与836,117名参与者的研究;使用JBI工具评估方法质量.
主要成果:
- 在NAFLD患者和健康对照人群之间,没有发现平均睡眠时间的显著差异.
- 长时间和短时间的睡眠时间与NAFLD (OR:0.8) 之间观察到一个显著的关联.
- 剂量反应元分析没有显示睡眠时间和NAFLD之间的线性或非线性关系.
结论:
- 睡眠时间的最高类别与NAFLD风险降低有关.
- 没有发现睡眠时间和NAFLD之间的总体剂量反应相关性.
- 进一步的研究可能会澄清睡眠和肝脏健康之间的复杂相互作用.
相关概念视频
Insufficient Sleep and Sleep Deprivation
130
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
130
Ultrasound II: Endoscopic Ultrasound and FibroScan
66
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
Endoscopic Ultrasound (EUS):
66
Overview of Lipid Metabolism
969
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
969
Substance Use Disorders Affecting Sleep
158
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
158
Diseases of the Liver and Gallbladder
418
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
418
Insomnia
78
Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
Multiple factors contribute...
Multiple factors contribute...
78


