使用分子对接和动态模拟来识别天然植物化学物质作为AKT2抑制剂,作为潜在的癌症治疗药物

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Jibon Kumar Paul1, Mahir Azmal1, Md Naimul Haque Shohan1

  • 1Department of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, 3114, Bangladesh.

Heliyon
|February 3, 2025
PubMed
概括

像米莱顿和乌扎里基宁这样的天然化合物显示出抑制AKT2的潜力,AKT2是癌症进展和治疗耐药性的关键驱动因素. 这些植物化学物质可以为癌症治疗和潜在的神经退行性疾病提供新的途径.

关键词:
在ATK2中使用ATK2.分子对接是分子对接.模拟分子动力学模拟瘤发生的发生因子.乌扎里基尼尼是一种原生素.

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