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Updated: May 29, 2025

In Vitro Enzyme Measurement to Test Pharmacological Chaperone Responsiveness in Fabry and Pompe Disease
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互补的远程和活性位点突变同时增强α-Galactosidase的催化活性和热稳定性

Zhuangzhuang Huang1, Junru Zhou1, Jialing Wang1

  • 1College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, 30 Puzhunan Road, Nanjing, Jiangsu 211816, China.

Journal of agricultural and food chemistry
|February 3, 2025
PubMed
概括

研究人员设计了一种α-galactosidase酶,克服了活性-稳定性权衡. 这种酶在工业应用中显示出更好的催化效率和热稳定性,特别是在加工拉芬家族的寡糖中.

关键词:
活动稳定性的权衡.计算机辅助设计是计算机辅助设计.在遥远的残留物中.基板结合式口袋袋可以绑定基板α-galactosidase的使用情况.

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Site-Directed Mutagenesis for In Vitro and In Vivo Experiments Exemplified with RNA Interactions in Escherichia Coli07:04

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