甲状腺和指甲黑色素瘤
Joseph A Masison1, Sherif A Eldirany2, Campbell L Stewart2
1University of Connecticut School of Medicine, Farmington, Connecticut, USA.
Clinics in dermatology
|February 3, 2025
概括
形形黑色素瘤 (ALM) 是手掌和脚的罕见皮肤癌. 早期检测和有针对性的治疗对于改善患者的生存和治疗结果至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
背景情况:
- 形晶状黑色素瘤 (ALM) 是一种罕见的,攻击性的皮肤恶性黑色素瘤亚型.
- 与其他黑色素瘤不同,ALM与紫外线辐射暴露无关.
- 它呈现出糟糕的生存预后和独特的临床特征.
研究的目的:
- 审查当前对状晶状质黑色素瘤的理解.
- 突出诊断挑战和及时诊断的障碍.
- 讨论改善患者治疗结果的潜在策略.
主要方法:
- 综合性文献审查,重点关注ALM.
- 发病率分析,诊断标准和他的病理学.
- 对皮肤镜和反射共聚焦显微镜特征的评估.
- 对基因组改变和当前治疗方式的审查.
- 包括最近的病例报告,说明诊断困难.
主要成果:
- ALM发生在部部位 (手掌,脚,下部位).
- 经常遇到诊断方面的挑战和延误.
- 基因组改变和治疗选择是正在进行的研究领域.
结论:
- 增加患者和医疗保健提供者的教育对于早期检测至关重要.
- 开发新的,有针对性的治疗方法至关重要.
- 迅速和准确的诊断对于改善ALM结果至关重要.
相关概念视频
Skin Cancer
3.0K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
3.0K
Changes in Skin Color: Clinical Perspectives
1.7K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
1.7K
Skin Diseases and Disorders
2.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
2.8K


