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Updated: May 29, 2025

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
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低循环线粒体DNA和增加的线粒激素表明系统性红斑狼与脏参与的系统性狼显著的线粒体功能障碍

Matthieu Halfon1, Ashfaque A Memon2, Anna Hedelius2

  • 1Transplantation Center, Lausanne University Hospital, Lausanne, Switzerland matthieu.halfon@chuv.ch.

Lupus science & medicine
|February 3, 2025
PubMed
概括

线粒体功能障碍标志物,包括全血线粒体DNA (mtDNA) 与核DNA (nucDNA) 的比例,在全身性红斑狼 (SLE) 中发生变化,特别是在脏参与的情况下. 增长分化因子15 (GDF-15) 可能表明SLE患者的疾病活性.

关键词:
自免疫性疾病 自免疫性疾病细胞因子 (cytokines) 是一种细胞因子.红斑狼,全身性 红斑狼狼性炎是一种神经炎症.

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