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Updated: May 29, 2025

A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy
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刺激激活的核糖核酶针对瘤微环境激活的癌症治疗的奇默体

Yuqi Zhang1, Jinfeng Zhu2, Ling Qiu3

  • 1State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, and Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, PR China.

Nature communications
|February 3, 2025
PubMed
概括

瘤微环境激活的核糖核酶向嵌合体 (TaRiboTACs) 在miR-21前降解,增强癌症放射治疗. 这种有针对性的方法改善了小鼠的瘤抑制.

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