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Updated: Jun 8, 2026

Label-Free Identification of Lymphocyte Subtypes Using Three-Dimensional Quantitative Phase Imaging and Machine Learning
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Label-Free Identification of Lymphocyte Subtypes Using Three-Dimensional Quantitative Phase Imaging and Machine Learning

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通过无标签多式非线性光学显微镜和机器学习加速生物制药细胞系选择

Jindou Shi1,2,3, Alexander Ho1,2,4, Corey E Snyder1,3

  • 1GSK Center for Optical Molecular Imaging, University of Illinois Urbana-Champaign, Urbana, IL, USA.

Communications biology
|February 3, 2025
PubMed
概括

使用无标签显微镜和机器学习,选择高性能生物制药细胞系的速度更快. 这种非扰动性方法可以在发育早期准确地识别细胞系.

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相关概念视频

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...