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Updated: May 12, 2026

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孕产妇的免疫激活在后代神经干细胞中印记了转化失调和差异MAP2酸化

Sandra M Martín-Guerrero1, María Martín-Estebané2, Antonio J Lara Ordóñez2

  • 1Centre for Cancer Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, UK.

Molecular psychiatry
|February 3, 2025
PubMed
概括

怀孕期间的孕产妇免疫激活 (MIA) 影响胎儿的大脑发育. 这项研究使用神经干细胞 (NSC) 揭示分子变化,特别是MAP蛋白酸化,影响神经功能和可塑性.

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相关概念视频

Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...