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Updated: May 29, 2025

A Fluorescence-based Assay for Characterization and Quantification of Lipid Droplet Formation in Human Intestinal Organoids
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A Fluorescence-based Assay for Characterization and Quantification of Lipid Droplet Formation in Human Intestinal Organoids

Published on: October 13, 2019

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戈尔吉凝结导致肠道脂质通过NEDD4通过HIF-1α介导的GM130无所不在的积累NEDD4通过GM130的积累

Hyunsoo Kim1, Channy Park1, Xiaofan Wei1

  • 1Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea.

Experimental & molecular medicine
|February 3, 2025
PubMed
概括

缺氧导致戈尔吉蛋白降解,导致戈尔吉凝结和小肠中的脂质积累. 抑制缺氧诱导因子1α (HIF-1α) 或NEDD4可以防止这种情况,减少脂质积累并改善脂质分泌.

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