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Updated: May 29, 2025

Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding
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类固醇激素受体 (NR3) 的化学基因组学

Espen Schallmayer1, Laura Isigkeit1, Lewis Elson1

  • 1Institute of Pharmaceutical Chemistry, Goethe-Universität Frankfurt, Frankfurt, Germany.

Communications chemistry
|February 3, 2025
PubMed
概括

一个新的化学遗传学图书馆有助于探索核受体3 (NR3) 功能. 该工具将药物效应与NR3受体活性联系起来,揭示了在自身免疫性疾病和神经退行等疾病中潜在的治疗应用.

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