心肌梗塞后的美托普罗罗尔暴露对未来心血管事件的影响:孟德尔的随机化研究

Lina Dorthea Bruun1, Geir Øystein Andersen2, Marianne Kristiansen Kringen3,4

  • 1Department of Pharmacology, Oslo University Hospital, Ullevål, PO BOX4956, Nydalen, Oslo, N-0424, Norway. linabruun@yahoo.no.

概括

代谢CYP2D6的遗传变异没有影响心脏病的结果,在心肌梗塞后接受梅托普罗罗尔治疗的患者. 这项研究发现,正常代谢者和中等/差代谢者之间在重大心血管不良事件或心血管死亡方面没有联系.

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