抑制MDM2与TP53改变的克隆性血液形成的出现有关

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Vishesh Khanna1,2, Gohar Eslami1,2, Rochelle Reyes1,2

  • 1Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.

NPJ precision oncology
|February 3, 2025
PubMed
概括

鼠类双分钟2 (MDM2) 抑制剂可能导致TP53克隆性血液形成,导致持续的全细胞衰竭. 这表明,在接受MDM2抑制剂治疗的患者中,骨髓瘤恶性瘤的潜在风险存在.

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