饮食中的植物化学指数和胆结石疾病的风险:一种病例对照研究
Mohammad Abdulmohsin Jebur1, Ghufran Lutfi Ismaeel2, Haitham Mukhklif Salim3
1College of Medicine, department of pathology and forensic medicine, Mustansiriyah University, Baghdad, Iraq. abdulmohsin.jebur.mohammad@gmail.com.
BMC gastroenterology
|February 3, 2025
概括
更高的饮食植物化学指数 (DPI) 与减少胆结石疾病 (GSD) 的风险有关. 增加富含植物化学物质的食物可能有助于预防胆结石,但需要进一步的研究.
科学领域:
- 营养科学 营养科学
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 饮食植物化学指数 (DPI) 估计了从食物中摄入的植物化学物质.
- 胆结石病 (GSD) 是一个严重的健康问题.
- 之前没有研究研究DPI和GSD风险之间的关联.
研究的目的:
- 调查饮食植物化学指数 (DPI) 与成年人胆结石病 (GSD) 风险之间的关系.
- 评估较高的DPI是否与较低的胆结石发病风险有关.
主要方法:
- 进行了一项病例对照研究,对250名胆结石患者和250名对照进行了对照.
- 使用经过验证的168项食品频率问卷计算DPI.
- 收集和分析了社会人口统计数据,体育活动,人体测量和饮食摄入量.
主要成果:
- DPI的最高三分位数与较低的胆结石风险显著相关 (OR=0.61,p=0.027).
- 在调整年龄和性别后,这种关联仍然存在.
- 即使考虑到多个混因素 (体力活动,BMI,吸烟,SES,能量摄入),最高DPI三位数仍然具有保护性 (OR=0.51,p=0.031).
结论:
- 饮食中的植物化学指数与胆结石风险之间存在负相关性.
- 摄入更多的富含植物化学物质的食物可能对预防胆结石有益.
- 需要进一步的研究来证实DPI和胆结石之间的联系.
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