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胰腺切除后的胰腺外分缺陷:一个系统性审查
Marcello Di Martino1,2, Ángela de la Hoz Rodriguez3, Andrea Saibanti4,5
1Department of Health Sciences, University of Piemonte Orientale, Novara, 28100, Italy. marcello.dimartino@uniupo.it.
BMC surgery
|February 3, 2025
概括
手术后的胰腺外分缺陷 (PEI) 诊断具有挑战性. 便弹性酶-1 (FE-1) 测试是常见的,但需要更多的研究来准确诊断和治疗指导.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
背景情况:
- 胰腺外分缺陷 (PEI) 由于胰腺功能降低而损害消化.
- 在胰腺切除后准确的PEI诊断仍然是一个临床挑战.
- 对于PEI诊断的既定指导方针往往没有被准确地遵循.
研究的目的:
- 审查胰腺切除后PEI的诊断工具.
- 评估可用的诊断测试的方法和准确性.
- 突出目前诊断实践中的差距.
主要方法:
- 使用结合文本和MeSH搜索策略进行了文献综述.
- 确定了专注于胰腺切除术后PEI诊断的相关文章.
- 分析了30项涉及2305名患者的研究.
主要成果:
- 在超过三分之二的研究中,PEI的发病率超过65%,这些研究涉及胰腺二切除术或远端胰腺切除术的患者.
- 便弹性酶-1 (FE-1) 是最常用的诊断测试.
- 与便脂肪或13C呼吸测试相比,FE-1没有显著的诊断准确性差异;在五项研究中报告了微量营养素缺乏.
结论:
- 在胰腺切除术后的PEI中,FE-1是最常用的诊断工具.
- 缺乏关于诊断准确性的高质量比较研究.
- 未来的研究应该专注于建立诊断标准和指导酶替代疗法.
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Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
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