膝关节骨关节炎和类似体重指数的人与没有膝关节骨关节炎的人之间的大腿肌肉脂肪透和身体功能差异:一个横截面研究
Jessica B Aily1, Marcos de Noronha2, Ricardo J Ferrari3
1Department of Physical Therapy, Federal University of São Carlos (UFSCar), Rodovia Washington Luís, km 235 - SP-310. São Carlos, São Paulo, CEP 13565-905, Brazil.
BMC musculoskeletal disorders
|February 3, 2025
概括
与没有OA的人相比,患有膝关节骨关节炎的个体具有更高的大腿肌内脂肪组织 (intraMAT) 和降低的身体功能. 需要进一步的研究来了解intraMAT的临床影响.
科学领域:
- 整形外科 整形外科 整形外科
- 放射学 放射学是一门学科.
- 生物医学工程 生物医学工程
背景情况:
- 膝关节关节炎 (OA) 与大腿脂肪组织增加有关,特别是肌际 (interMAT) 和肌内 (intraMAT).
- 之前的研究没有充分解决膝关节OA和非OA组之间的MAT内和MAT间的BMI匹配比较.
- 这项研究研究了膝关节骨质炎患者的股骨脂肪组织组成和身体功能,控制BMI.
研究的目的:
- 为了比较膝关节OA和没有膝关节OA的个体之间的大腿内MAT和间MAT体积,与BMI相匹配.
- 评估两组之间的身体功能差异,包括膝盖伸展强度和自我报告的结果.
- 探索 intraMAT,interMAT 和膝关节OA中的身体功能之间的关系.
主要方法:
- 年龄≥40岁的参与者被分为膝关节OA (KL等级2-3) 和未受影响的组,与BMI (±1 kg/m2) 相匹配.
- 量化了厚内MAT和interMAT体积的量.
- 独立的t测试比较了包括WOMAC分数,身体功能测试和膝盖伸展强度在内的结果.
主要成果:
- 46名参与者 (每组23人) 完成了这项研究.
- 与未受影响组相比,膝关节骨质炎组的MAT内含量显著增加 (p <0.05),但MAT间含量并没有明显增加.
- 膝盖OA组表现出更糟糕的自我报告结果,身体功能较差,膝盖伸展强度降低.
结论:
- 膝关节OA的特点是高 intraMAT和减弱的身体功能.
- 这些发现强调了需要进一步调查膝关节OA中的intraMAT的临床相关性.
- 向intraMAT可能为改善膝关节OA患者的身体功能提供一种新的治疗方法.
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