在可重编程的功能表面上进行多模分离和反转运输滴
Ming Liu1, Runan Chen1, Jin Yuan1
1Advanced Research Institute of Multi-Disciplinary Sciences, Beijing Institute of Technology, Beijing 100081, China.
Langmuir : the ACS journal of surfaces and colloids
|February 4, 2025
概括
这项研究引入了一种可重编程滴滴操纵的新技术,通过磁场产生的可移动可湿度梯度,在单一表面上实现多式分割和运输.
科学领域:
- 表面科学是一门科学.
- 微流体学 微流体学
- 材料科学是一种材料科学.
背景情况:
- 滴滴分裂和运输对于生物化学分析和无菌操作至关重要.
- 目前的方法受到固定表面微观结构的限制,阻碍了可控制的操纵.
- 可重新编程的表面用于滴滴控制仍然是一个重大挑战.
研究的目的:
- 开发一种灵活的技术,用于在单一表面上进行多式液滴分裂和反转运输.
- 为了创建一个可重编程的表面微观结构,可控制的湿度.
- 调查滴滴操纵的机制和影响因素.
主要方法:
- 制造一个嵌入磁性颗粒和软化剂的聚合物矩阵,然后浸入滑剂.
- 使用外部磁场生成可移动的湿度梯度.
- 滴滴分裂机制的理论分析和运输行为的实验研究.
主要成果:
- 在单一表面上展示了多式联接液滴分裂和反转运输.
- 通过调节磁场参数来实现可重编程的表面湿透性和微观结构.
- 确定了滴滴分裂和运输的关键条件和影响因素.
结论:
- 开发的技术提供了一个多功能平台,用于可重新编程的滴滴激活.
- 这种方法为微流体和生物分析设备提供了一个新型原型.
- 对于高级应用程序,可以精确控制滴滴行为.
相关概念视频
02:13Overview of Transposition and Recombination
Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
01:14Introduction to Nuclear Reprogramming
Nuclear reprogramming is the process of switching gene expression of one cell type to that of another cell type, usually from a differentiated cell state to an undifferentiated cell state. Differentiation occurs during processes such as development and morphogenesis, tissue regeneration, and malignancy. Cells can also be artificially induced to reprogram their gene expression by techniques such as nuclear transfer, induced pluripotency, and cell fusion. Such techniques have many applications in...
01:24Methods of Nuclear Reprogramming
Nuclear reprogramming is a process of transforming one cell type into an unrelated cell type by epigenetic changes that alter the cell’s original gene expression pattern. Such epigenetic changes force cells to express a different set of genes, which play a significant role in inducing transformation into other cell types. Nuclear reprogramming offers applications in reproductive cloning for livestock propagation and regenerative medicine — developing patient-specific cells for injury repair.
01:22Block Diagram Reduction
The process of deriving the transfer function of a control system often involves reducing its block diagram to a single block. This simplification can be achieved through a series of strategic operations, including relocating branch points and comparators. These operations preserve the overall function of the system while allowing for easier manipulation and combination of blocks.
The first step in this process is the identification and relocation of a branch point. A branch point, where a...
The first step in this process is the identification and relocation of a branch point. A branch point, where a...
01:24Fast Decoupled and DC Powerflow
The fast decoupled power flow method addresses contingencies in power system operations, such as generator outages or transmission line failures. This method provides quick power flow solutions, essential for real-time system adjustments. Fast decoupled power flow algorithms simplify the Jacobian matrix by neglecting certain elements, leading to two sets of decoupled equations:
01:29Downstream Processing
Downstream processing begins once fermentation is complete and involves a series of steps to recover and purify products such as acids, vitamins, antibiotics, or proteins.Cell HarvestingFor example, for intracellular protein-based products, the first step is harvesting the cells. This is typically achieved using centrifugation or filtration to separate the cells from the liquid phase.Cell Disruption for Intracellular ProductsIf the target product is intracellular, the harvested cells must be...