Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Pore Transport and Ion-Pair Transport01:17

Pore Transport and Ion-Pair Transport

335
Pore transport and ion-pair formation are critical mechanisms for the absorption and distribution of drugs in the body.
Pore transport, also known as convective transport, is a process where small molecules like urea, water, and sugars rapidly cross cell membranes as though there were channels or pores in the membrane. Although direct microscopic evidence is limited  but the concept of pores or channels is widely accepted based on physiological evidence. Despite the lack of direct...
335
Dialysis01:15

Dialysis

576
Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
576
Colloids and Suspensions01:17

Colloids and Suspensions

1.7K
Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles visible to the naked eye or seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. The suspended particles in a suspension settle out after some time of mixing. The separation of particles from a suspension is...
1.7K
Viscosity01:17

Viscosity

5.8K
When water is poured into a glass, it falls freely and quickly, whereas if honey or maple syrup is poured over a pancake, it flows slowly and sticks to the surface of the container. This difference in the flow of different kinds of liquids arises due to the fluid friction between the liquid layers and the liquid and the surrounding material. This property of fluids is called fluid viscosity. In this example, water has a lower viscosity than honey and maple syrup.
The SI unit of viscosity is...
5.8K
Passive Diffusion: Overview and Kinetics01:17

Passive Diffusion: Overview and Kinetics

377
Passive diffusion is a critical process that allows small lipophilic drugs to cross the cell membrane along a concentration gradient. This mechanism's efficiency depends on four primary factors: the membrane's surface area, the drug's lipid-water partition coefficient, the concentration gradient, and the membrane's thickness.
When administered orally, drugs establish a substantial concentration gradient between the gastrointestinal (GI) lumen and the bloodstream, expediting...
377
Steady, Laminar Flow Between Parallel Plates01:17

Steady, Laminar Flow Between Parallel Plates

124
Understanding steady, laminar flow between parallel plates is essential for analyzing and designing flow in narrow rectangular channels, commonly found in various water conveyance and drainage systems. The Navier-Stokes equations govern fluid motion and are generally challenging to solve due to their nonlinearity. However, simplifications are possible in certain cases, like the steady laminar flow between parallel plates. For this scenario, we assume steady, incompressible, laminar flow.
124

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

How deep is deep enough? The importance of the detection limits of the CML minimal residual disease gDNA assay.

Cell death discovery·2026
Same author

TMEM230 and mitochondrial regulation in Alzheimer's disease.

International review of neurobiology·2026
Same author

A Spatiotemporal Physics-Motivated State-Space Model of Lake Temperature Profiles.

Environmental science & technology·2026
Same author

A unified framework for assessing water quality indices under data and model weight uncertainty.

Water research·2026
Same author

Stochastic model for mixing interface evolution through three-dimensional fracture networks.

Physical review. E·2025
Same author

Ataluren improves hematopoietic and pancreatic disorders in Shwachman-Diamond syndrome patients: a compassionate program case-series.

Nature communications·2025

相关实验视频

Updated: May 29, 2025

Confocal Imaging of Confined Quiescent and Flowing Colloid-polymer Mixtures
10:56

Confocal Imaging of Confined Quiescent and Flowing Colloid-polymer Mixtures

Published on: May 20, 2014

12.1K

拦截历史驱动孔隙介质中的合体运输变异

Sabrina N Volponi1, Bashar M Al-Zghoul1, Giovanni Porta2

  • 1Civil and Environmental Engineering and Earth Sciences, University of Notre Dame, Notre Dame, Indiana 46556, United States.

Environmental science & technology
|February 4, 2025
PubMed
概括
此摘要是机器生成的。

在多孔介质中预测合体运输被一个新的模型所彻底改变,该模型专注于谷物拦截历史,而不仅仅是谷物通过. 这种方法准确地模拟了非指数衰变,改善了复杂的环境和生物医学环境中的预测.

关键词:
合物合物是一种合物.拦截 拦截 拦截没有指数的非指数.透的媒介是多孔的保持个人资料的保留档案.交通运输运输运输运输运输运输运输运输运输不良的情况是不利的.

更多相关视频

Transport of Surface-modified Carbon Nanotubes through a Soil Column
10:26

Transport of Surface-modified Carbon Nanotubes through a Soil Column

Published on: April 2, 2015

9.4K
Frugal Imaging Technique of Capillary Flow Through Three-Dimensional Polymeric Printing Powders
06:01

Frugal Imaging Technique of Capillary Flow Through Three-Dimensional Polymeric Printing Powders

Published on: October 4, 2022

1.2K

相关实验视频

Last Updated: May 29, 2025

Confocal Imaging of Confined Quiescent and Flowing Colloid-polymer Mixtures
10:56

Confocal Imaging of Confined Quiescent and Flowing Colloid-polymer Mixtures

Published on: May 20, 2014

12.1K
Transport of Surface-modified Carbon Nanotubes through a Soil Column
10:26

Transport of Surface-modified Carbon Nanotubes through a Soil Column

Published on: April 2, 2015

9.4K
Frugal Imaging Technique of Capillary Flow Through Three-Dimensional Polymeric Printing Powders
06:01

Frugal Imaging Technique of Capillary Flow Through Three-Dimensional Polymeric Printing Powders

Published on: October 4, 2022

1.2K

科学领域:

  • 环境科学环境科学
  • 生物医学工程 生物医学工程
  • 物理化学 物理化学

背景情况:

  • 在多孔介质中的合体运输传统上使用基于经过的粒度的指数式衰变模型.
  • 排斥性屏障抑制附着,导致非指数的合物度衰变,目前的模型无法预测.
  • 在实验中观察到的非指数趋势表明了一个基本的,但尚未解决的传输过程.

研究的目的:

  • 在合体运输建模中提出一个范式的转变.
  • 为非指数式合体衰变开发一个预测框架.
  • 在具有排斥性屏障的环境中增强合体运输预测.

主要方法:

  • 修改分数删除的原则,从"每粒通过"改为"每粒拦截".
  • 将粮食拦截历史纳入运输模型.
  • 验证新的框架与显示非指数衰变的实验数据相对应.

主要成果:

  • 拟议的模型准确地预测了非指数的合物度与距离的衰变.
  • 该框架成功地解释了排斥性屏障对合体运输的影响.
  • 通过考虑拦截历史,建立了一个简单而有预测性的方法.

结论:

  • 转向模拟每次拦截的分数损失,而不是每次经过的粒度,提供了一个更准确的合体运输预测框架.
  • 这种新的视角使得在以前具有挑战性的环境中,如具有排斥性屏障的环境中,能够准确地预测合体运输.
  • 这些发现对地下水保护和药物输送系统有重大影响.