在横截图成像技术中评估炎症性肠病的活动和严重程度:系统性审查
Arianna Dal Buono1,2, Francesco Faita3, Alessandro Armuzzi1,2
1IBD Center, Department of Gastroenterology, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy.
Journal of Crohn's & colitis
|February 4, 2025
概括
像MRE和IUS这样的截面成像可以准确地评估炎症性肠病 (IBD) 的活性和严重程度. 这些技术有望在IBD管理和临床试验中得到广泛应用.
科学领域:
- 胃肠病学 胃肠病学
- 放射学 放射学是一门学科.
- 医疗成像医学成像
背景情况:
- 炎症性肠病 (IBD) 管理越来越依赖于横截面成像.
- 这些技术包括肠道超声波 (IUS),计算机断层扫描 (CTE) 和磁共振 (MRE).
- 评估疾病活动和严重程度对于有效的IBD患者护理至关重要.
研究的目的:
- 系统地审查IBD疾病活动和严重程度评估的横截面成像证据.
- 为这些成像模式的最佳利用提供指导.
- 评估IUS,CTE和MRE与参考标准相比的准确性.
主要方法:
- 对PubMed,EMBASE和Scopus数据库进行系统审查.
- 包括在2023年12月之前发表的评估成像技术与参考标准 (内镜,组织病理学,手术) 的研究.
- 分析了179项涉及10,988名IBD患者的研究,重点关注疾病活动和严重程度评估.
主要成果:
- 包括了179项研究 (1990-2023年),包括10,988名IBD患者.
- 经常评估MRE (101项研究) 和IUS (39项研究),以及CTE (22项研究).
- 聚合的灵敏度,特异性和准确性在IUS,MRE和CTE方面从60%到100%不等.
结论:
- 截面成像技术在评估IBD活动和严重程度方面表现出中等到良好的准确性.
- 磁共振肠道学 (MRE) 和肠道超声学 (IUS) 特别突出其潜力.
- 这些成像方法被建议在临床实践和IBD临床试验中得到更广泛的应用.
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