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使用益生菌Lactiplantibacillus plantarum GP258合成的ZnO纳米颗粒的表征

Prashantkumar Siddappa Chakra¹, Aishwarya Banakar², Shriram Narayan Puranik²

¹Department of Studies in Microbiology, Davangere University, Davangere, Karnataka, 577007, India.

Beilstein journal of nanotechnology

|February 4, 2025

概括

使用乳酸细菌的氧化纳米颗粒 (ZnO NPs) 的可持续合成产生了稳定的10nm颗粒. 这些ZnO NP具有显著的抗菌和抗增殖特性,可用于医学和材料科学.

科学领域:

纳米技术纳米技术
微生物学微生物学
材料科学材料科学材料科学

背景情况:

为纳米粒子开发可持续和环保的合成方法至关重要.
生物合成为传统的化学方法提供了一种绿色的替代方案.
氧化纳米颗粒 (ZnO NPs) 由于其独特的特性,具有多样化的应用.

研究的目的:

为了合成ZnONP,使用乳酸细菌从奶酪作为生物剂.
以其物理,化学和结构性质来表征合成的 ZnO NPs.
评估合成的 ZnO NPs 的抗菌,抗增殖,光催化和电化学潜力.

主要方法:

生物合成ZnONP利用乳酸细菌进行减少和封闭.
通过XRD,FTIR,UV-Vis,TEM,SEM-EDX和泽塔电位分析进行表征.
使用MTT测定对抗人类病原体的抗菌活性和抗增殖作用的评估.

主要成果:

成功合成了六边形的石结构ZnONP,平均尺寸为10nm.
体系统表现出高稳定性,其泽塔电位为-60mV.
观察到显著的抗菌活性,特别是针对金黄色葡萄球菌,有望的抗增殖潜力,IC50为98.53μg/mL.

结论:

乳酸细菌为ZnO NP合成提供了有效和可持续的途径.
合成的 ZnO NPs 显示出强大的抗菌和抗增殖活性.
在药物输送,癌症研究和涂料方面的潜在应用是由光催化和电化学分析表明的.

关键词:

这是一种抗癌药物.绿色合成是一种绿色合成.乳酸细菌是一种乳酸细菌.纳米颗粒是一种纳米粒子.氧化氧化的使用方法

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