多发性硬化症中疲劳,呼吸功能,平衡和核心肌肉形态之间的相关性:一项全面的观察性研究
Marta De La Plaza San Frutos1, Ismael Sanz-Esteban1,2, Federico Salniccia1,2
1Department of Physiotherapy, Faculty of Medicine, Health and Sports, European University of Madrid, Madrid, Spain.
Frontiers in neurology
|February 4, 2025
概括
在多发性硬化症 (MS) 中,更好的呼吸功能和腹肌强度与更好的平衡和减少疲劳相关. 这些发现表明,有针对性的干预措施可以提高MS患者的身体表现和生活质量.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 生理学 生理学 生理学
背景情况:
- 多发性硬化症 (MS) 与疲劳,呼吸功能受损和平衡缺陷有关.
- 这些因素与MS中核心肌肉功能之间的相互作用尚未完全理解.
- 超声波成像提供了一种新的方法来评估腹肌与MS的功能结果相关的腹肌.
研究的目的:
- 研究MS患者的疲劳,呼吸功能,平衡和超声波评估的腹肌特征之间的关系.
- 确定核心肌肉的强度和功能是否与MS的呼吸能力和姿势稳定性相关.
- 为MS制定针对性康复策略提供信息.
主要方法:
- 一项涉及27名被诊断患有多发性硬化症的参与者的横截面研究.
- 使用修改疲劳影响量表 (MFIS) 评估疲劳.
- 呼吸功能的测量 (强迫生命能力 - FVC,1秒内强迫呼气体积 - FEV1) 和平衡 (伯格平衡量 - BBS,干部损伤规模动态 - TIS DYN).
- 腹部和腹膜肌的超声波成像.
- 使用斯皮尔曼的相关性分析,显著水平为p<0.05.
主要成果:
- 在呼吸功能和平衡之间观察到显著的相关性.
- 强迫生命能力 (FVC) 与BBS中度相关 (r=0.443).
- 1秒内强迫呼气量 (FEV1) 与BBS的相关性很高 (r=0.500),与TIS DYN的相关性中等 (r=0.427).
- 疲劳 (MFIS) 与BBS (r=-0.402) 有负相关性.
- 腹部肌肉的强度和功能,特别是内部斜,与体的稳定性和姿势控制有关.
结论:
- 呼吸功能和腹肌特征与MS患者的平衡和疲劳有显著的关联.
- 旨在改善呼吸功能的干预措施可能会对平衡产生积极影响,并减少疲劳.
- 这些发现强调了整体治疗MS的重要性,包括呼吸和核心强化炼,以提高功能结果和生活质量.
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