上呼吸道指标预测阻塞性睡眠呼吸暂停严重性的能力:系统性审查
Yara M Taha1, Shaimaa M Abu El Sadat1, Ramy M Gaber1
1Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Ain Shams University, Cairo 11566, Egypt.
Dento maxillo facial radiology
|February 4, 2025
概括
上呼吸道测量显示,与阻塞性睡眠呼吸暂停 (OSA) 严重程度的相关性较弱. 最小的横截面积和体积是最有希望的,但仍然是OSA的弱预测因素.
科学领域:
- 放射学和睡眠医学 睡眠医学
- 医学成像分析 医学成像分析
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 诊断和严重程度评估受到空气道狭窄的不一致发现的挑战.
- 了解上呼吸道解剖学与OSA严重程度之间的关系对于有效管理至关重要.
研究的目的:
- 系统地审查有关上呼吸道测量和OSA严重性之间的相关性的现有文献.
- 通过CT成像来研究OSA严重性的各种上呼吸道尺寸的预测值.
主要方法:
- 在PubMed,Scopus和Web of Science进行了系统的文献搜索,寻找在OSA患者中将上呼吸道测量与呼吸暂停-呼吸暂停指数 (AHI) 相关联的研究.
- 分析了形光束CT (CBCT) 或多探测器CT (MDCT) 成像数据,并使用纽卡斯尔-太华尺度评估了研究质量.
- 来自14项涉及720名患者的合格研究的结果被描述性地综合.
主要成果:
- 上呼吸道的长度显示出与AHI的微弱到中度的正相关性.
- 最小的横截面积显示了可变的相关性,从强烈的负面到没有.
- 鼻和上呼吸道总体体积表现出与AHI的微弱至中度负相关性.
结论:
- 最小的横截面积和上呼吸道体积显示了最有希望的,尽管仍然很弱的,与OSA患者的AHI相关性.
- 用CBCT或MDCT测量的上呼吸道长度,横截面积和体积通常是OSA严重性的弱预测指标.
- 可能需要进一步的研究来确定更强大的成像生物标志物来确定OSA严重程度.
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