CCR2信号调节呼吸道中抗克拉米迪亚T细胞免疫反应

Shuaini Yang1, Jinxi Yu1, Xue Dong2

  • 1Key Laboratory of Immune Microenvironment and Disease, Tianjin Institute of Immunology, Department of Immunology, School of Basic Medical Sciences, Tianjin Key Laboratory of Cellular and Molecular Immunology, Tianjin Medical University, Tianjin, China.

PLoS pathogens
|February 4, 2025
PubMed
概括

化基因受体CCR2通过促进 Th1 保护性免疫反应,对控制 Chlamydia 呼吸道感染至关重要. 缺少它会导致严重的肺炎和增加的易感性,原因是受损的Th1细胞功能和增强的Th2/Th17反应.

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