发展中国家糖尿病紧急情况的规模,风险因素和经济影响:系统性审查
Halefom Kahsay Haile1, Teferi Gedif Fenta2
1Department of Pharmacy, College of Medicine and Health Sciences, Adigrat University, Tigray, Ethiopia.
PloS one
|February 4, 2025
概括
像DKA和HHS这样的糖尿病紧急情况正在发展中国家上升,这是由感染和不遵守驱动的. 有针对性的预防对于减少住院和经济负担至关重要.
科学领域:
- 内分泌学和新陈代谢学
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
背景情况:
- 糖尿病酸性酸症 (DKA),高血糖性超性综合征 (HHS) 和严重的低血糖症是危及生命的糖尿病紧急情况.
- 发展中国家糖尿病的患病率越来越高,加剧了这些代价昂贵的并发症的影响.
- 关于这些紧急情况的大小,成本和预测因素的有限数据使资源有限的环境中的管理变得复杂.
研究的目的:
- 系统地审查发展中国家糖尿病紧急情况的规模,风险因素和经济影响.
- 为资源有限的医疗保健机构提供数据,以改善管理策略.
主要方法:
- 按照PRISMA (2020) 准则进行系统审查.
- 在PubMed,EMBASE,Cochrane和Scopus搜索了2000-2023年间的研究.
- 通过叙事合成分析了40项符合条件的研究,将成本标准化为2023美元.
主要成果:
- 流行率:每年发生DKA (3.8%-73.4%),HHS (0.9%-58%),严重的低血糖 (3.3%-64.7%).
- 常见的危险因素包括感染,新发糖尿病和不遵守规定.
- 每次事件的直接住院费用从105美元到230美元不等.
结论:
- 发展中国家不断增加的糖尿病紧急情况需要紧急的预防性干预,重点是感染,不遵守规定和新发糖尿病.
- 识别高风险个体是减少紧急诊所和住院治疗的关键.
- 将预防策略纳入糖尿病管理中至关重要,以改善结果并减轻医疗保健系统的经济压力.
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