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小分子BCL6抑制抑制毛囊T辅助细胞分化和血爆裂形成

Rens Kraaijeveld1, Dennis A Hesselink1, Marjolein Dieterich1

  • 1Erasmus MC Transplant Institute, Department of Internal Medicine, Division of Nephrology & Transplantation, University Medical Center Rotterdam, Rotterdam, the Netherlands.

Human immunology
|February 4, 2025
PubMed
概括

该BCL6抑制剂79-6抑制T毛囊辅助体 (Tfh) 和B细胞反应,显著减少抗体的产生. 这种化合物通过抑制Tfh和B细胞相互作用,有望在移植后预防免疫反应.

关键词:
一切都是为了活跃.抗体是一种抗体.抗体介导排斥是一种抗体介导的排斥.B 细胞 B 细胞 B 细胞在 BCL6 中.小分子抑制剂小分子抑制剂细胞Tfh细胞Tfh细胞转录因子 转录因子移植 移植 移植 移植

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