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Updated: Jul 24, 2026

Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump
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Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump

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一种新的HPLC方法,用于同时估计纳他素和沃里康纳,用于眼部药物输送应用

Velmurugan Kailasam1, Oindrilla Dasgupta1, Tamizhmathy Mannangatty1

  • 1Translational Pharmaceutics Research Laboratory (TPRL), Department of Pharmacy, Birla Institute of Technology and Sciences (BITS), Pilani, Hyderabad Campus, Hyderabad, Telangana 500078, India.

Journal of pharmaceutical and biomedical analysis
|February 4, 2025
PubMed
概括

一种新的,经过验证的逆相高性能液态染色学 (RP-HPLC) 方法允许同时定量纳塔amycin和voriconazole. 这种方法对于分析用于治疗真菌角膜炎的协同抗真菌组合至关重要.

关键词:
分析方法验证的分析方法验证.药物配送组合药物交付方式纳塔米辛是一种天然酸盐.同时估计的估计.沃里康纳 (Voriconazole) 是一种可以

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A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials06:18

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Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...
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Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...