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Updated: May 29, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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最近PKC抑制剂开发的进展:结构设计策略和治疗应用

Wen Li1, Kun Zhu1, Yuyin Liu1

  • 1Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, China.

European journal of medicinal chemistry
|February 4, 2025
PubMed
概括

开发选择性蛋白激酶C (PKC) 抑制剂仍然具有挑战性. 药物设计的最新进展,包括基于片段的和全的方法,为治疗癌症和糖尿病等疾病提供了有前途的新支架.

关键词:
抑制剂 抑制剂 抑制剂在 PKC PKC 里面,药理学活动 药理学活动结构与活动的关系.合成化合物 合成化合物

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