内分泌干扰化学物质,血液代谢和表观遗传学对乳腺癌风险的影响:一个多维的门德尔随机化研究

Ningning Song1, Xinquan Xi1, Kuan Yang2

  • 1Department of Breast Surgery, Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Shushan District, Hefei, Anhui 230022, PR China.

概括

环境内分泌干扰化学物质 (EDC),如 parabens 和 phthalates 显示与乳腺癌亚型的特定关联. 咖啡酸硫酸和甲基酸盐可能会调解这些效应,突出显示Luminal A和三阴性乳腺癌 (TNBC) 的潜在生物标志物.

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