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气管,支气管和肺癌在老年人中的全球流行病学趋势
Jintu Chen1, Caili Li2, Yang Yu3
1Department of Clinical Laboratory, Quanzhou First Hospital Affiliated to Fujian Medical University, No. 248 East Street, Quanzhou City, Fujian 362000, PR China.
Cancer epidemiology
|February 4, 2025
概括
在老年人中,全球气管,支气管和肺癌 (TBL) 病例从1992年至2021年增加,尽管发病率下降. 在东亚和高SDI地区的女性中观察到更高的负担.
科学领域:
- 流行病学 流行病学
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
背景情况:
- 气管,支气管和肺癌 (TBL) 主要影响老年人群.
- 对于TBL癌症存在有限的流行病学数据,特别是在老年人中.
- 这项研究解决了在这个人口群体中对TBL癌症的最新全球流行病学见解的需求.
研究的目的:
- 确定60岁及以上个体的TBL癌症的全球流行病学概况.
- 分析全球TBL癌症负担的空间和时间趋势.
- 确定与老年TBL癌症相关的关键风险因素和人口统计模式.
主要方法:
- 使用的全球疾病负担 (GBD) 2021年60岁以上的个人数据.
- 根据社会人口指数 (SDI),性别和年龄评估全球TBL癌症影响.
- 分析了年龄标准化发病率 (ASIR),死亡率 (ASMR) 和根据残疾调整的寿命年 (DALY) 率 (ASDR),包括年平均百分比变化 (AAPC).
主要成果:
- 从1992年到2021年,老年人中的TBL癌症病例,死亡和DALY增加,但ASIR,ASMR和ASDR却下降.
- 东亚在2021年显示出相当大的负担;西撒哈拉以南非洲在过去30年中出现了显著的增长.
- 在老年人中,吸烟和颗粒物空气污染是TBL癌症死亡和DALY的主要风险因素.
结论:
- 结核病癌症负担呈现出显著的区域和人口统计学差异.
- 较高的SDI地区和女性需要对TBL癌症的预防和管理给予更多的关注.
- 了解这些趋势对于改善老年TBL癌症患者的三级预防,诊断和治疗策略至关重要.
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