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Updated: Jun 14, 2025

Assessment of Child Anthropometry in a Large Epidemiologic Study

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Published on: February 2, 2017

儿童肥胖临床试验中的种族和民族差异

Catherine G Coughlin¹, Emilie S Zoltick², Fatima Cody Stanford³

¹Division of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.

Obesity (Silver Spring, Md.)

|February 4, 2025

概括

历史上被边缘化的种族和种族群体,除了黑人和西班牙裔儿童,在儿科肥胖临床试验中代表性不足. 改善多样性和种族/种族数据报告对于公平的研究至关重要.

科学领域:

临床研究是临床研究.
儿科卫生健康儿科卫生健康
卫生公平性健康公平性

背景情况:

儿童肥胖是一个重大的公共卫生问题.
临床试验对于开发有效的肥胖治疗方法至关重要.
确保多样化的参与者代表性对于概括性和公平性至关重要.

研究的目的:

评估美国儿科肥胖临床试验中历史上被边缘化的种族和民族群体的代表性.
为了确定与疾病患病率相比,入学率的差异.
突出种族和民族数据收集和报告中的差距.

主要方法:

在clinicaltrials.gov.gov注册的儿科肥胖试验的横截面分析.
包括2013年1月至2023年8月在美国完成的试验.
计算入学率-流行率差异 (EPD) 来量化代表性不足.

主要成果:

260项试验符合资格;49.2%报告了种族/种族数据.
白人,西班牙裔和黑人儿童的入学率通常反映了疾病负担.
亚洲,美洲印第安人/阿拉斯加原住民和夏威夷原住民/太平洋岛民儿童的比例明显低 (EPD < 0).

结论:

在儿科肥胖试验中,几个边缘化群体的代表性显著不足,表明需要改善参与者多样性.
种族和种族信息的记录和报告存在重大差距.
需要采取协调一致的努力来加强数据收集,并确保在临床试验中充分代表性.

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