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相关概念视频

Skin Cancer01:30

Skin Cancer

3.0K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
1.7K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

2.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Tumor Immunotherapy01:27

Tumor Immunotherapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
464
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
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iPS Cell Differentiation01:22

iPS Cell Differentiation

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The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
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[Medical care situation of people with vitiligo : A pilot and feasibility study on guideline-oriented management in German dermatology practices].

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相关实验视频

Updated: May 29, 2025

Direct Reprogramming of Mouse Fibroblasts into Melanocytes
09:38

Direct Reprogramming of Mouse Fibroblasts into Melanocytes

Published on: August 27, 2021

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[关于病变发生,诊断和治疗的更新]

Paloma Seidel1, Markus Böhm2

  • 1Klinik für Hautkrankheiten, Universitätsklinikum Münster, Von-Esmarch-Str. 58, 48149, Münster, Deutschland.

Dermatologie (Heidelberg, Germany)
|February 4, 2025
PubMed
概括

白风是一种皮肤脱色的疾病,涉及黑色素细胞的破坏,并与自身免疫反应有关. 一种新的局部Janus激酶抑制剂为非细分性白提供了一种特定的治疗方法.

科学领域:

  • 皮肤病学 皮肤病学
  • 免疫学 免疫学 免疫学
  • 药理学 药理学是指药理学的学科.

背景情况:

  • Vitiligo 是一种常见的皮肤疾病,由于黑色素细胞的破坏导致脱色.
  • 非细分性白风 (NSV) 是一种慢性自身免疫性疾病,涉及T细胞激活和免疫记忆.
  • 目前的白风治疗方法有限,这凸显了改善患者护理和新疗法的需要.

研究的目的:

  • 审查目前对白风病原学的理解,重点关注干扰素特征的作用.
  • 讨论白风治疗的最新进展,包括批准新的特定疗法.
  • 突出非细分性白风患者新疗法选择的重要性.

主要方法:

  • 关于白风病原和治疗选择的文献综述.
  • 对新型白风疗法最近的临床试验数据的分析.
  • 专注于干扰素通路和Janus激酶抑制剂在白病中的作用.

主要成果:

  • 干扰素签名在白风的病理生物学中起着关键作用.
  • 局部雅努斯激酶 (JAK) 抑制剂,如鲁克索利提尼布,代表了一类新的白风特异性疗法.
  • 鲁克索利提尼布已被批准用于治疗非细分性白风 (NSV).
关键词:
卡尔辛尤林抑制剂 卡尔辛尤林抑制剂伴随性疾病 伴随性疾病简氏酶抑制剂 简氏酶抑制剂照相疗法 照相疗法 照相疗法局部使用的皮质类固醇.

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相关实验视频

Last Updated: May 29, 2025

Direct Reprogramming of Mouse Fibroblasts into Melanocytes
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Direct Reprogramming of Mouse Fibroblasts into Melanocytes

Published on: August 27, 2021

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A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
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结论:

  • 对白风病原体的新见解导致了向治疗的开发.
  • 局部JAK抑制剂的批准标志着在管理NSV方面取得了重大进展.
  • 改善治疗选择对于提高白风患者的生活质量至关重要.