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下丘脑区域的深度大脑刺激:一个系统的审查

Mohammad Mofatteh^1,2, Abdulkadir Mohamed^3,4, Mohammad Sadegh Mashayekhi^5,6

¹School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK. mmofatteh01@qub.ac.uk.

Acta neurochirurgica

|February 4, 2025

概括

下丘脑的深度大脑刺激 (DBS) 在儿童和成人中显示出治疗各种耐火性疾病的前景,包括头痛和攻击性. 需要进一步的研究来确认其长期的安全性和有效性.

科学领域:

神经调节是一种神经调节.
神经外科神经外科
神经科学是一个神经科学.

背景情况:

下丘脑是一个关键的大脑区域,调节重要功能.
深度大脑刺激 (DBS) 是神经系统疾病的治疗选择.
脑下垂体DBS正在研究治疗不耐药的疾病.

研究的目的:

系统地审查下丘脑DBS目标.
为了确定下丘脑DBS的适应症.
总结下脑下垂体DBS的主要临床发现.

主要方法:

对人类下丘脑DBS的研究进行系统审查.
在PubMed,Scopus和Web of Science数据库中进行了搜索.
遵守PRISMA研究选择指南.

主要成果:

分析了超过二十年的34项研究 (412名患者).
症状包括难治性头痛,侵略性和阿尔茨海默病.
后下丘脑是最常见的目标,51.7%的人报告症状改善.

结论:

低垂体DBS可用于儿童和成人患者的选择性耐火性疾病.
需要进行进一步的大规模研究.
长期安全性和有效性数据需要验证.

关键词:

攻击性侵略性攻击性在 DBS 中,DBS 是 DBS 的代名词.深度大脑刺激是什么?脑下垂体核的核心下丘脑的下丘脑是什么意思耐火性头痛耐火性头痛是一种

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