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非药物干预对癌症认知功能的影响:系统性审查的概述
Darren Haywood1,2,3,4, Ashley M Henneghan5,6, Alexandre Chan7
1Human Performance Research Centre, INSIGHT Research Institute, Faculty of Health, University of Technology Sydney (UTS), Driver Avenue, Moore Park, Sydney, NSW, 2021, Australia. darren.haywood@uts.edu.au.
概括
非药物干预有效改善与癌症相关的认知障碍 (CRCI). 认知训练显示了最强有力的证据,而运动是有希望的,尽管有变化. 进一步的研究应该为CRCI干预标准化报告和定义.
科学领域:
- 在瘤学瘤学.
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
背景情况:
- 癌症幸存者经常经历与癌症相关的认知障碍 (CRCI),影响日常功能.
- 越来越多地探索非药理干预措施来管理CRCI.
研究的目的:
- 批判性地审查现有的关于CRCI非药物干预的系统性审查.
- 确定有效的干预措施和研究缺口,以告知临床实践和指导方针.
主要方法:
- 进行了对系统性审查 (SRs) 的综合审查.
- 在六个数据库中进行了搜索,包括在开放科学框架和PROSPERO.上预先注册.
- 包括64个评估癌症患者认知改善的非药物干预措施的SR.
主要成果:
- 认知训练/康复证明了最强有力的证据,证明了提高认知的有效性.
- 身体活动/运动显示出有希望的结果,但具有相当大的变化.
- 心身和心理/行为疗法具有有限但短期的有效性;多模式干预显示出潜力,但定义不佳.
结论:
- 非药物干预对于改善与癌症相关的认知障碍是有效的.
- 未来的研究应该集中于协调报告准则和定义认知领域.
- 调查与疗效相关的干预和参与者特征对于推进CRCI研究至关重要.
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