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Updated: May 29, 2025

Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs
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全长度mRNA测序解决了在人类CD4 T细胞激活过程中表达的基因在5' UTR长度中的新奇变异

Cassandra R Woolley1, Julia H Chariker2, Eric C Rouchka3,4

  • 1Department of Microbiology and Immunology, University of Louisville School of Medicine, Louisville, KY, USA.

Immunogenetics
|February 4, 2025
PubMed
概括

长读异形测序 (Iso-Seq) 揭示了激活的人类CD4T细胞中广泛的转录变异. 许多基因表现出延长的5'未翻译区域 (UTR),影响RNA稳定性和蛋白质表达.

关键词:
5′未翻译区域 (UTR)已激活的CD4 T细胞在CXCR5中,CXCR5是CXCR5.异形序列化 (Iso-Seq) 是一种方法.这就是PacBio.

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