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Updated: May 29, 2025

CRISPR Gene Editing Tool for MicroRNA Cluster Network Analysis
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多个位置的CRISPRi向与单个截断的指导RNA向.

Molly M Moore1, Siddarth Wekhande1, Robbyn Issner1

  • 1Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Nature communications
|February 5, 2025
PubMed
概括

研究人员开发了一种CRISPR干扰 (CRISPRi) 方法,使用截断的指南有效选数千个潜在的转录因子结合位点. 这种方法有助于理解基因调节及其在细胞功能和疾病中的作用.

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