经过延迟的直肠解剖后的长期肠功能:多中心队列研究 (GRECCAR) 的分析
Maxime K Collard1, Jean-Jacques Tuech2, Charles Sabbagh3
1Department of Colorectal Surgery, Hôpital Saint-Antoine, Assistance Publique Hôpitaux de Paris, Sorbonne University, Paris, France.
概括
延迟直肠缩 (DCAA) 为60%的患者提供了良好的长期肠功能,由于结果不佳,不到5%的患者需要永久性静脉口腔. 这项研究评估了DCAA.
科学领域:
- 结肠直肠外科手术是什么意思
- 外科手术的结果
- 胃肠病学 胃肠病学
背景情况:
- 延迟结直肠解剖 (DCAA) 是一种用于结直肠手术的手术技术.
- 肠道功能的改变可能是影响DCAA后患者生活质量的重大限制.
研究的目的:
- 在接受DCAA.患者的大型多中心队列中评估长期的肠功能.
- 为了确定影响DCAA后肠功能结果的因素.
主要方法:
- 在29个医院 (2010-2021) 进行DCAA的患者的回顾性分析.
- 低前切除综合征 (LARS) 评分和因肠功能不佳而产生的口腔形成的评估.
- 良好的肠功能被定义为保存的肠连续性,没有或轻微的LARS.
主要成果:
- 60%的患者 (n=146) 在32个月的中位随访后报告了良好的长期肠功能 (没有LARS或轻微LARS).
- 40%的患者 (n=146) 经历了肠功能不佳,包括LARS (36%) 和绝对静脉口腔 (4%).
- 没有任何测试的变量,包括先前的放射治疗或静脉漏,在DCAA后预测肠道功能不佳.
结论:
- 大多数患者 (60%) 在DCAA后达到令人满意的肠功能.
- 很少有百分比 (<5%) 需要由于DCAA后的功能障碍而进行永久性静脉口腔.
- 这项研究强调了DCAA的长期功能结果,这些结果通常是有利的.
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