软软的机器人心脏与心肌带形成,用于心脏功能
Daiki Ueda1, Koichi Suzumori1, Hiroyuki Nabae1
1Department of Mechanical Engineering, School of Engineering, Institute of Science Tokyo, Meguro-ku, Japan.
Soft robotics
|February 5, 2025
概括
研究人员根据心肌带理论创建了一个软的机器人心脏模型. 这种创新型号模仿了真实的心脏功能,为心力衰竭和手术治疗提供了潜在的见解.
科学领域:
- 生物医学工程 生物医学工程
- 心血管生理学心血管生理学
- 软机器人软机器人 软机器人软机器人
背景情况:
- 了解心脏的射出分数机制对于医学至关重要.
- 心肌收缩率约为20%,而喷射率超过60%.
- 目前对心脏运动机制的知识仍然不完整.
研究的目的:
- 根据心肌带理论开发心脏的功能模型.
- 用人造肌肉复制腹腔结构和功能.
- 研究软机器人心脏在临床应用中的潜力.
主要方法:
- 使用螺旋心肌带理论创建了一个功能模型.
- 薄薄的麦基本人造肌肉嵌入在软弹性质中.
- 该模型被卷以复制心室结构,并测试了喷射分数和压力产生.
主要成果:
- 软机器人心脏的收缩率为17.3%,弹射率为47.8%.
- 机器人心脏的厚度变化接近动物心脏 (1.28倍).
- 水喷射实验显示最大压力为200mmHg,类似于人类心脏压力-体积循环.
结论:
- 软软的机器人心脏密切模仿真心脏的关键生理参数.
- 这个模型显示了阐明心力衰竭病理生理学的潜力.
- 该技术可能有助于开发用于心脏病的新型手术治疗方法.
相关概念视频
Structure of Cardiac Muscles
Cardiac muscle, or myocardium, is a specialized type of muscle found exclusively in the heart. Its unique structural and functional characteristics enable the heart to perform its vital role of pumping blood throughout the body continuously and rhythmically. The cardiac muscle cells, or cardiomyocytes, possess an endomysium and perimysium but do not have an epimysium.
Compared to skeletal muscles, cardiac muscle cells are small and mostly have a single nucleus. Additionally, they are usually...
Compared to skeletal muscles, cardiac muscle cells are small and mostly have a single nucleus. Additionally, they are usually...
Specialized Characteristics of Cardiac Muscles
The primary role of cardiac muscles is to propel blood throughout the cardiovascular system. The cardiac muscle cells, or cardiomyocytes, exhibit specialized characteristics that allow them to perform this function.
Cardiac muscle cells are smaller than skeletal muscles, averaging 10–20 mm in diameter and 50–100 mm in length. However, they have large energy demands for continuous contraction and relaxation. This energy is almost exclusively derived from aerobic metabolism of energy reserves in...
Cardiac muscle cells are smaller than skeletal muscles, averaging 10–20 mm in diameter and 50–100 mm in length. However, they have large energy demands for continuous contraction and relaxation. This energy is almost exclusively derived from aerobic metabolism of energy reserves in...
Layers of the Heart Wall
The heart wall comprises three distinct layers: the epicardium, myocardium, and endocardium. The outermost layer, the epicardium, is the visceral layer of the serous pericardium, featuring a thin, transparent mesothelial surface and an inner layer of areolar connective tissue with fat deposits that increase with age.
The myocardium, the thickest layer, consists of cardiac muscle cells interconnected by intercalated discs and crisscrossing connective tissue fibers. These muscle fibers contract...
The myocardium, the thickest layer, consists of cardiac muscle cells interconnected by intercalated discs and crisscrossing connective tissue fibers. These muscle fibers contract...
Development of the Heart
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...


