胎盘微血管架构 在正常和先天性心脏病怀孕中成像
Peiwen Chen1, Sheng Zhao1, Liqun Sun2,3
1Department of Ultrasonography, Maternal and Child Health Hospital of Hubei Province, Wuhan, China.
概括
MV-FlowTM成像显示,胎盘血管减少胎儿与先天性心脏病 (CHD),特别是那些心脏外形 (EXM),在第三个三个月. 这项技术有助于了解患有心血管疾病的怀孕中胎盘异常.
科学领域:
- 周围生理学 周围生理学
- 胎儿医学 胎儿医学
- 心脏病学 心脏病学
背景情况:
- 先天性心脏病 (CHD) 影响胎儿发育,并可能与心脏外形 (EXM) 相关.
- 胎盘血管架构在胎儿福祉中起着至关重要的作用.
- 评估胎盘输液对于管理高风险怀孕至关重要.
研究的目的:
- 用MV-FlowTM成像在胎儿与孤立的心脏病,心脏病与EXM,和正常怀孕评估胎盘血管性.
- 分析不同胎盘区域内的血管分布.
- 在这些组中,将胎儿多普勒参数和生长与胎盘输液相关联.
主要方法:
- MV-FlowTM成像评估了227名正常胎儿和139名心血管疾病 (妊娠年龄11-41周) 的胎盘微血管结构.
- 胎盘血管指数 (VIMV %) 在上,中和下胎盘段进行测量.
- 记录了胎儿多普勒指数 (动脉,中脑动脉,静脉管,子宫动脉) 和大脑胎盘比率.
主要成果:
- 与对照组相比,患有CHD和EXM的胎儿在所有胎盘区域都显示出显著较低的VIMV %.
- 在第三季度,整体的CHD组在上半身和中半身的胎盘部分呈现了VIMV %的降低.
- 在整个心脏病组中,多普勒指数有显著差异;单独的心脏病中,血管管脉动指数是唯一显著的差异.
结论:
- MV-FlowTM成像显示,胎盘血管性降低胎儿心脏病 (单独和EXM) 在第三个三个月.
- 这种成像模式可以提高对心血管疾病监测中的胎盘发育异常的理解.
- MV-FlowTM的连续应用可能有利于胎儿心声监测CHD怀孕.
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