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韩国佩杰特骨疾病的流行病学
Jung-Wee Park1,2, Dong-Hoon Lee1, Ki-Tae Park1
1Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seongnam 463-707, South Korea.
JBMR plus
|February 5, 2025
概括
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科学领域:
- 骨改造和帕杰特骨病 (PDB) 的流行病学.
- 老年医学和慢性疾病管理.
- 对骨疾病的药物监督和治疗坚持.
背景情况:
- 帕杰特骨病 (PDB) 是一种慢性骨疾病,在全球范围内患病率各不相同.
- 包括韩国在内的亚洲人口的GDP数据特别稀缺.
- 了解PDB流行病学对于有针对性的公共卫生干预至关重要.
研究的目的:
- 从2010年至2020年全面评估韩国PDB的流行病学.
- 调查PDB发病率趋势,骨分布,并发病症和双酸盐利用情况.
- 为了提供对PDB管理和患者结果的洞察力,在一个代表性不足的地区.
主要方法:
- 韩国医疗保险审查和评估数据库 (2010-2020) 的回顾性分析.
- 使用ICD-10代码 (M880,M888,M889) 识别了4252名PDB患者.
- 发病率的评估,年龄和性别分层的趋势,受影响的部位,并发症和双酸盐使用.
主要成果:
- 2015年后,PDB发病率在男性中出现下降,但在女性中显著增加.
- 脊椎 (23.5%) 和骨盆/股骨 (17.0%) 是受影响最常见的部位.
- 观察到低二酸盐使用 (9.8%),尽管PDB的慢性性质.
结论:
- 韩国的PDB发病率较低,但越来越高,特别是在女性中.
- 在PDB患者中注意到高并发症率 (例如胃炎,GERD).
- 双酸盐的使用不足凸显了需要改善PDB管理和意识的必要性.
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