月经周期作为一个生命体征:一个全面的审查
Ana K Rosen Vollmar1, Shruthi Mahalingaiah2,3, Anne Marie Jukic1
1National Institute of Environmental Health Sciences, Epidemiology Branch, Durham, NC, 27709, USA.
F&S reviews
|February 5, 2025
概括
月经周期应该被视为一个人一生中的一个重要标志,从初潮到更年期. 追踪月经模式为妇科和整体健康提供了宝贵的见解,影响健康和疾病预测.
科学领域:
- 生殖健康 生殖健康
- 妇女健康 妇女健康
- 内分泌学 在内分泌学.
背景情况:
- 月经周期被认为是一种生命体征,但其记录并不是标准的临床或研究实践.
- 生命体征对于预测健康结果,指导治疗和监测患者进展至关重要.
- 现有的生命体征有助于识别病理,确认健康状况,并对环境暴露作出反应.
研究的目的:
- 审查支持将月经周期归类为生命标志的科学证据.
- 为了证明月经周期模式如何满足生命体征的标准.
- 突出月经周期在从初潮到更年期的健康评估中的作用.
主要方法:
- 使用关键词和受控词汇进行了全面的文献搜索.
- 优先进行系统审查,元分析和临床实践指南.
- 审查了月经周期作为健康指标及其与健康结果的关联的证据.
主要成果:
- 月经周期作为一个关键的健康指标,周期性地影响各种健康状况.
- 月经周期模式与更年期后的长期健康结果有关.
- 证据支持月经周期对暴露的反应性及其在优化健康方面的实用性.
结论:
- 月经周期符合标准,可以被认为是整个生殖生命中的重要标志.
- 将月经周期视为一个重要标志是理解妇科和一般健康的未充分利用的工具.
- 现有工具和资源用于记录月经周期,以帮助临床和研究实践.
相关概念视频
Hormonal Regulation of the Menstrual Cycle
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
Ovarian Cycle
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle length...
Hormonal Control of the Ovarian Cycle
The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
The Menstrual Cycle
The menstrual cycle is a recurrent sequence of changes in the uterine endometrium, specifically its functional layer, the stratum functionalis. This cycle prepares the uterus for potential pregnancy. This cycle typically spans 21–35 days, averaging 28 days, and aligns with the ovarian cycle, regulated by fluctuating levels of ovarian hormones, primarily estrogen and progesterone.
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a uterine...
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a uterine...
Menses Phase
The uterine cycle begins with the menstrual phase, which is considered day one of the cycle and typically lasts about five days. This phase is characterized by the degeneration and shedding of the stratum functionalis, the functional layer of the endometrium.
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...
Secretory Phase
The secretory phase of the menstrual cycle, spanning from day 14 to 28 in a typical 28-day cycle, is a period of significant physiological changes in the female reproductive system. This phase commences immediately after ovulation and is characterized by the preparation of the endometrium for potential embryo implantation.
Following ovulation, the corpus luteum, a temporary endocrine structure, produces progesterone and estrogens. These hormones stimulate the growth and coiling of endometrial...
Following ovulation, the corpus luteum, a temporary endocrine structure, produces progesterone and estrogens. These hormones stimulate the growth and coiling of endometrial...


