膝关节骨关节炎管理的最新进展:叙述性综述
Viktor Shtroblia1, Pavlo Petakh2, Iryna Kamyshna3
1Department of General Surgery, Uzhhorod National University, Uzhhorod, Ukraine.
Frontiers in medicine
|February 5, 2025
概括
有效地管理膝关节骨关节炎 (OA) 疼痛需要个性化,多模式的方法. 本综述详细介绍了当前的治疗方法,强调局部疗法和非药物干预作为缓解疼痛和改善生活质量的关键初始策略.
科学领域:
- 整形外科 整形外科 整形外科
- 类风湿病学 类风湿病学
- 疼痛管理 疼痛管理
背景情况:
- 膝关节关节炎 (OA) 是一种普遍的疾病,导致严重的疼痛,生活质量下降和大量的医疗费用.
- 膝关节骨髓炎疼痛的有效管理需要一个全面和个性化的治疗策略.
研究的目的:
- 为膝盖OA疼痛提供当前治疗选择的概述.
- 评估膝关节OA疼痛管理的各种治疗方式的疗效,安全性和临床效用.
主要方法:
- 对当前关于膝盖骨关节炎疼痛治疗的文献进行系统审查.
- 分析治疗选择,包括局部药物,口服止痛药,关节内注射,营养补充剂,非药物干预和新兴生物药物.
主要成果:
- 局部治疗 (NSAIDs,素) 和非药物干预 (运动,减肥) 显示出初始管理的前景,具有有利的安全性.
- 口服止痛药具有有限的疗效和显著的副作用,只适合短期使用.
- 关节内注射,营养补充剂和非药物方法提供了可变的益处,应根据患者个体需求量身定制.
- 向生物制剂显示出潜力,但需要进一步研究以实现常规临床应用.
结论:
- 个性化,组合治疗对于最佳的膝关节OA疼痛管理至关重要.
- 持续的研究对于开发更安全,更有效的治疗膝关节OA疼痛的方法至关重要.
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