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高压氧气疗法改善了系统性类固醇治疗对突然的感觉神经听力损失的效果

Yu-Ching Chen¹, Yu-Hsi Liu^2,3, Bor-Hwang Kang^2,4,5,6

¹Division of Plastic and Reconstructive Surgery, Department of Surgery, Kaohsiung Veterans General Hospital, No.386, Dazhong 1st Rd., Zuoying Dist., Kaohsiung City, 813414, Taiwan, ROC.

|February 5, 2025

概括

综合高压氧气疗法 (HBOT) 和类固醇治疗显著改善了突然感觉神经听力损失 (SSNHL) 的结果. 早期的HBOT治疗,特别是对于患有严重听力损失的年轻患者,会产生最佳的结果.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
高压医学高压医学
听力学听力学是指听力学.

背景情况:

突然感觉神经听力损失 (SSNHL) 是一种需要迅速和有效治疗的关键病症.
标准治疗通常涉及全身类固醇 (SS),但结果可能是可变的.

研究的目的:

评估将高压氧气疗法 (HBOT) 与SSNHL的全身类固醇 (SS) 疗法相结合的治疗疗效.
确定患者子组和治疗参数,以优化SSNHL的结果.

主要方法:

在2017年8月至2022年7月期间诊断出SSNHL的505名患者的回顾性分析.
患者被分为两组:仅接受SS治疗的患者和接受SS加HBOT治疗的患者.
使用纯色音量计 (PTA) 和响应率来评估听力改善.

主要成果:

与SS单独组相比,SS + HBOT组在低频率下PTA值的改善明显更好 (P = 0.007).
在SS + HBOT组中观察到更高的响应率 (≥15dB和≥25dB的改善) (分别P=0.002和P<0.001).
在初始听力损失>50dB的患者和年轻人中,HBOT在较低频率的听力损失方面表现出特别有效.

结论:

结合HBOT和SS疗法可以提高SSNHL治疗的有效性.
最佳的结果与在诊断后11天内启动HBOT并接受大约五次会议有关.
HBOT提供了显著的好处,特别是对于特定的患者人口统计学和听力损失特征.

关键词:

高压氧疗法高压氧疗法这是一种类固醇.突然的感官神经神经听力损失.治疗方法治疗方法

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