在接受剖腹产的妇女中,作为术后止痛药的德佐辛与埃斯凯他明相比
1Department of Anesthesiology, Affiliated Maternity and Child Health Care Hospital of Nantong University, Nantong 226007, Jiangsu, China.
African journal of reproductive health
|February 5, 2025
概括
素有效地管理剖腹产后的术后疼痛,减少疼痛得分和产后抑郁症. 这种止痛药为女性提供了安全和有益的选择,而不会增加不良影响.
科学领域:
- 麻醉学 麻醉学
- 产科 产科 产科 产科 产科
- 精神病学是一个精神病学.
背景情况:
- 剖腹产后的术后疼痛管理对于康复至关重要.
- 患者控制的静脉静脉止痛 (PCIA) 是一种常见的止痛方法.
- 评估新型止痛药,如埃斯凯他明,对于改善患者的治疗结果至关重要.
研究的目的:
- 为了研究胺作为术后止痛药在接受剖腹产的妇女的疗效.
- 在这个患者群体中,比较esketamine与dezocine的止痛作用.
- 评估胺对术后康复和产后抑郁症的影响.
主要方法:
- 一项涉及134名剖腹产患者的比较研究.
- 根据自愿选择,患者被划分为两组:为PCIA,以斯基坦胺 (n=112) 或德佐辛 (n=22).
- 使用视觉模拟尺度 (VAS) 评估疼痛,并记录出行走和排尿时间等恢复参数. 爱丁堡产后抑郁量表 (EPDS) 用于评估抑郁症.
主要成果:
- 与德佐辛组相比,在手术后12小时和24小时,埃斯凯坦胺组的VAS得分明显较低 (P<0.05).
- 在乙胺组 (P<0.05) 中观察到较早的首次排便时间,而在行走或排尿时间没有显著差异.
- 虽然两组都显示了手术后EPDS得分的增加,但与德佐辛组相比,乙胺组的得分明显较低 (P<0.05). 在不良反应中没有发现显著差异.
结论:
- 素是剖腹产患者的有效术后止痛药,与dezocine相比,可以提供更好的缓解疼痛.
- 胺使用与改善的康复标志物和显著减少产后抑郁症症状有关.
- 在这种人群中,石胺似乎是手术后疼痛管理的安全选择,而不会增加不良影响.
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