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对AAV基因组喷射的生物物理和结构见解.

Keely Gliwa1, Joshua Hull1, Austin Kansol1

  • 1Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida, USA.

Journal of virology
|February 5, 2025
PubMed
概括

复合腺相关病毒 (rAAV) 基因组喷射发生在高于囊分解的温度下,低pH值和VP1/VP2缺失加速了这一过程,以提高基因治疗载体的效率.

关键词:
卡普西德 (Capsid) 是一种体.低温电磁波冷却器 (Cryo-EM) 是一个非常好的方法.基因组 基因组是基因组的组成部分.稳定的稳定性 稳定的稳定性结构 结构 结构 结构

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