生活必需品8和心力衰竭风险之间的关联:卡伊卢安研究的发现
Yang Liu1, Maoxiang Zhao2, Jinguo Jiang3
1Department of Epidemiology and Biostatistics, School of Public Health, Peking University, 38# Xueyuan Road, Haidian District, Beijing 100191, China.
European journal of preventive cardiology
|February 5, 2025
概括
改善生活必需品8 (LE8) 评分与心力衰竭 (HF) 的风险降低有关. 即使最初LE8水平较低的个体也可以通过改进来降低其HF风险.
科学领域:
- 心血管健康 心血管健康
- 预防性心脏病学 预防性心脏病学
- 公共卫生 公共卫生
背景情况:
- 生活必需品8 (LE8) 和心力衰竭 (HF) 风险之间的关系尚未得到充分证实.
- 了解LE8如何影响HF对于制定有效的预防策略至关重要.
研究的目的:
- 调查LE8不同指标与心力衰竭发病率之间的关联.
- 评估LE8轨迹和心力衰竭风险状态的预测值.
主要方法:
- 分析了35,896名没有HF病史的参与者的数据.
- 使用潜混合物建模 (2006-2014) 识别LE8轨迹.
- 考克斯的比例危险模型用于评估HF风险,包括LE8状态,年变化率和轨迹.
主要成果:
- 确定了五个不同的LE8轨迹,其中与降低HF风险相关的上升趋势 (HR 0.43).
- 无论是LE8状态还是轨迹,都显示出与HF风险的反向关联.
- 与单独的LE8状态相比,LE8轨迹对HF风险的预测准确度更高.
结论:
- LE8与心力衰竭风险相反相关.
- 改善LE8得分,即使从低基线开始,也可以减轻HF风险.
- LE8轨迹提供了有价值的预后信息,用于识别高风险高的个体.
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