在怀孕同时患有高血压的患者中,母性动脉弹性的变化
Qianyu Lan1, Shasha Liu1, Qianqian He2
1Department of General Internal Medicine, The Fourth Hospital of Shijiazhuang, No. 16 Tangu North Street, Shijiazhuang, 050031, Hebei, China.
Archives of gynecology and obstetrics
|February 5, 2025
概括
回声追踪 (ET) 技术可以通过评估动脉弹性来诊断与高血压 (PCH) 并发的妊娠. ET参数和内皮功能的变化可靠地预测孕妇PCH的发展.
科学领域:
- 心血管生理学心血管生理学
- 产科 产科 产科 产科 产科
- 医疗成像医学成像
背景情况:
- 血管内皮功能障碍可以使用回声追踪 (ET) 技术检测到.
- 对于与高血压 (PCH) 并发的怀孕常规ET检测的诊断实用性仍然不清楚.
研究的目的:
- 调查ET在诊断孕妇PCH中的有效性.
- 评估动脉弹性的变化,并预测PCH发生.
主要方法:
- 使用ET超声波系统来评估动脉弹性.
- 测量了氧化物 (NO) 和内甲素-1 (ET-1) 的血水平.
- 采用接收机操作特征曲线分析和回归分析进行预测和相关性.
主要成果:
- 与正常怀孕相比,患有PCH的孕妇在血压和蛋白尿中表现出显著的差异.
- ET参数 (PWVβ,β-刚性,Eρ,AC) 和内皮功能标志物 (减少NO,增加ET-1) 有显著差异.
- 这些ET参数和标记可靠地预测PCH的发生,并表明尾管内皮功能受损.
结论:
- ET参数和尾内皮功能指数是PCH的可靠预测指标.
- 常规的ET检测可以帮助怀孕妇女诊断PCH.
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