恶性黑色素瘤的肺转移显示了地面玻璃不透明的结节
Keisuke Todoroki1, Satoshi Kawakami2, Yukiko Kiniwa3
1Department of Radiology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan. ktodoroki@shinshu-u.ac.jp.
Japanese journal of radiology
|February 5, 2025
概括
恶性黑色素瘤的肺转移可以在CT扫描上以地面玻璃不透明结节 (GGNs) 的形式出现. 瘤翻倍时间可能有助于区分这些GGN与肺腺癌.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 肺部医学 肺部医学
背景情况:
- 恶性黑色素瘤通常会转移到肺部.
- 肺转移可以在计算机断层扫描 (CT) 上呈现各种成像特征.
- 地玻璃不透明结节 (GGNs) 是黑色素瘤肺转移的一个不太常见的表现.
研究的目的:
- 为了确定恶性黑色素瘤的肺转移中的地面玻璃不透明结节 (GGNs) 的频率.
- 描述这些GGN的成像特征,包括瘤翻倍时间和与黑色素瘤亚型的关联.
- 评估GGN模仿或与原发性肺腺癌区分的潜力.
主要方法:
- 354名患有恶性黑色素瘤的患者胸部CT扫描的回顾性审查.
- 包括87名确诊肺转移的患者.
- 评估结节性 (GGN与固体),瘤翻倍时间和黑色素瘤亚型 (粘膜,皮肤,状).
主要成果:
- 在14.9%的黑色素瘤肺转移中发现了地面玻璃不透明结节 (GGNs).
- 与固体结节 (43.8天) 相比,GGN显示瘤翻倍时间稍长 (52.0天).
- GGNs与粘膜黑色素瘤相比,与状黑色素瘤或皮肤黑色素瘤更为频繁.
结论:
- 恶性黑色素瘤的肺转移可以在CT上表现为GGN,发生在14.9%的病例中.
- 瘤翻倍时间是黑色素瘤肺转移成GGN和原发性肺腺癌之间的潜在区别.
- GGNs与粘膜黑色素瘤的关联需要进一步调查.
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